Sex determination: the female soccer team

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In C. elegans as well as in P. pacificus sex is determined by the ratio of X chromosomes to autosomes. XX animals develop as hermaphrodites, X0 animals are males. However, there are mutants that show a sex reversal:

  • In tra(transformer)-mutants, XX animals look like males
  • In a fem or her mutant background X0 animals have a female or hermaphrodite appearence, respectively.


To do

To read

A. Pires-daSilva & R.J. Sommer Conservation of the global sex determination gene tra-1 in distantly related nematodes Genes & Development 18:1198-1208(2004)



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